1 Assessing the Performance of Different High - density Tiling Microarray Strategies for Mapping Transcribed Regions of the Human Genome
نویسندگان
چکیده
1 Department of Molecular Biophysics and Biochemistry, Yale University, New Haven CT 06520-8114, USA 2 Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven CT 06520-8103, USA 3 Department of Genetics, Yale University School of Medicine, New Haven, CT 06520–8005, USA 4 Department of Computer Science, Yale University, New Haven, CT 06520-8285, USA 5 Center for Nanotechnology, NASA Ames Research Center, Moffett Field, CA 94035, USA * To whom correspondence should be addressed: E-mail: [email protected] (M.S.), [email protected] (M.G.) + Present address: Stockholm Bioinformatics Center, AlbaNova University Center, Stockholm University, SE-10691 Stockholm, Sweden
منابع مشابه
Assessing the performance of different high-density tiling microarray strategies for mapping transcribed regions of the human genome.
Genomic tiling microarrays have become a popular tool for interrogating the transcriptional activity of large regions of the genome in an unbiased fashion. There are several key parameters associated with each tiling experiment (e.g., experimental protocols and genomic tiling density). Here, we assess the role of these parameters as they are manifest in different tiling-array platforms used for...
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